商品信息
產(chǎn)品英文名稱 | Human Transferrin protein |
產(chǎn)品中文名稱 | 重組人轉(zhuǎn)鐵蛋白(TF) |
別名 | PRO2086 Protein; TFQTL1 Protein; HEL-S-71p Protein, Human; PRO1557 Protein; Transferrin Protein,Siderophilin, partially saturated |
商品屬性
標簽 | 無標簽 |
種屬 | 人 |
序列 | Amino acid sequence derived from Human Transferrin protein isoform (P02787, Met 1-Pro 698) with a polyhistidine tag at the C-terminus was expressed. |
活性 | 檢測進行中 |
蛋白長度 | 重組人轉(zhuǎn)鐵蛋白由690個氨基酸組成,預測分子量為76.6 kDa。 在還原條件下,SDS-PAGE中人轉(zhuǎn)鐵蛋白的表觀分子量約為70-100 kDa。 |
純度 | ≥ 95 % ,使用SDS-PAGE檢測 |
特點&優(yōu)勢 | 采用 LAL 法檢測,每 1 μg 蛋白質(zhì)中的 EU 含量小于 1.0。 |
產(chǎn)品形式 | 凍干粉,凍干緩沖液為無菌的 PBS,pH 7.4。 |
基因ID | 7018 |
蛋白序列鏈接 | /uniprot/P02787 |
使用中注意事項 | 開蓋使用前,請先離心。本產(chǎn)品為凍干粉,推薦用該產(chǎn)品配套的Reconstitution Buffer進行復溶,且濃度不低于100 µg/mL??蛻艨筛鶕?jù)后續(xù)的實驗需求,進行進一步的稀釋。 |
保存建議 | 本產(chǎn)品為凍干粉形式,建議:將凍干粉的重組人轉(zhuǎn)鐵蛋白(TF)產(chǎn)品保存于-20℃以下的干燥環(huán)境中。本產(chǎn)品溶解之后,可在4℃保存2-7天,長期使用請置于-20℃以下。為長期保存,推薦添加載體蛋白(0.1% HSA或者BSA),并酌情分裝保存,避免反復凍融。 |
運輸條件 | 常溫運輸 |
警告 | 本文列出的產(chǎn)品僅供研究使用,不適用于人類或臨床診斷。我們產(chǎn)品所推薦應用,不是建議使用我們的產(chǎn)品去違反任何或許可證。對于使用本產(chǎn)品可能發(fā)生的侵權或其他違規(guī)行為,我們不承擔任何責任。 |
附加信息
背景 | Transferrin (Tf),is an iron transporter, which is mainly biosynthesized in the liver, and it can also be biosynthesized in the brain; i.e., by oligodendrocytes and the choroid plexus, cerebrospinal fluid (CSF) producing tissue. The CSF contains two Tf isoforms, brain-type Tf and serum-type Tf, which differ in their glycan structures. Brain-type Tf is uniquely glycolsylated with biantennary asialo- and agalacto-complex type N-glycans that carry bisecting β1,4-GlcNAc and core α1,6-Fuc.The glycans of serum-type Tf in the CSF are similar to those of Tf in serum. Biochemical analyses reveal that the apparent molecular size of brain-type Tf is smaller than that of serum-type Tf, and that hydrophobic patches are exposed on brain-type Tf as demonstrated by hydrophobic probe binding studies. Research indicates that brain-type Tf levels is decreased in idiopathic normal pressure hydrocephalus, in which CSF production is suspected to decrease, while brain-type Tf increased in spontaneous intracranial hypotension, in which CSF production is suspected to increase. These results suggest that brain-type Tf could be a biomarker of altered CSF production. |
圖片及說明

Fig.SDS-PAGE analysis of Human Transferrin protein.
免責聲明:以上所展示的信息由企業(yè)自行提供,內(nèi)容的真實性、準確性和合法性由發(fā)布企業(yè)負責,化工儀器網(wǎng)對此不承擔任何保證責任。
亞科因(武漢)生物技術有限公司
相關供應
- 重組人單核細胞趨化蛋白2,SUMO-標簽(
- 重組人骨形態(tài)發(fā)生蛋白9,S-標簽(BMP-9
- 重組病毒棘突蛋白RBD,His-標簽(無動
- 重組人骨形態(tài)發(fā)生蛋白3(BMP-3)
- 重組人骨形態(tài)發(fā)生蛋白13(BMP-13)
- 重組人/小鼠/大鼠Activin A蛋白(Activ
- 重組人Noggin蛋白(Noggin)
- 重組人骨形態(tài)發(fā)生蛋白2(BMP-2)
- 重組人骨形態(tài)發(fā)生蛋白4(BMP-4)
- 重組小鼠骨形態(tài)發(fā)生蛋白4(BMP-4)
- 重組人骨形態(tài)發(fā)生蛋白15,His-標簽(BM
- 重組小鼠骨形態(tài)發(fā)生蛋白4,His-標簽(B