PermeGear在線單元是一種流動(dòng)型的單元，用來替代Bronaugh單元，它的孔徑尺寸從3mm到15mm。它們由3M公司的Kel-F塑料制成或者是Daikin公司的氟塑料制成。在線單元有一個(gè)*的固定夾持系統(tǒng)可以起到預(yù)設(shè)、可重復(fù)的、安全的固定生物組織或膜。該固定系統(tǒng)讓用戶提前將供給體上部通過不銹鋼的彈簧提供壓力壓在膜上使之密封，孔徑密封直徑在0.1mm內(nèi)。高效液相色譜（HPLC）的連接件使用內(nèi)徑為1/16”的管子。在單元內(nèi)的攪動(dòng)效應(yīng)可以用我們獨(dú)有的雙流轉(zhuǎn)變系統(tǒng)（Twin-Flow Conversion System）進(jìn)行檢查。

   PermeGear在線單元及在線自動(dòng)透皮擴(kuò)散系統(tǒng)合并了12個(gè)單元為一個(gè)在線的全自動(dòng)單元，一個(gè)供應(yīng)調(diào)速蠕動(dòng)泵，一個(gè)連續(xù)收集器，一個(gè)恒溫水浴循環(huán)加熱單元，一個(gè)自動(dòng)控制器組成了一個(gè)功能強(qiáng)大的滲透現(xiàn)象分析系統(tǒng)，可以分析大批量的樣品以節(jié)省時(shí)間。我們的自動(dòng)控制器允許用戶收集16個(gè)樣品并能在連續(xù)99.9小時(shí)內(nèi)同時(shí)做在線自動(dòng)分析。每一個(gè)樣品的時(shí)間可以通過收集器進(jìn)行獨(dú)立的程序設(shè)定。可根據(jù)用戶的選擇確定收集瓶的數(shù)量。我們提供20ml 28mm直徑的收集瓶,允許用戶選擇使用其它常用的4ml WISP管。

PermeGear’s Automated Systems incorporate In-Line Cells, a peristaltic pump, a fraction collector, and a heater/circulator into a versatile system for analyzing flux over time. Collection vials are at the option of the user, racks for 20ml 28mm diameter scintillation vials are provided. Adapters are available to allow the use of many different vials including the popular 4ml WISP vials. Because of the varied requirements of individual users, vials ARE NOT supplied by PermeGear.

All PermeGear automated diffusion cell systems are based on the continuous flow principle. A multi-channel peristaltic pump draws receptor solution from a reservoir through a distribution manifold and sends it to the In-Line Cells. The cells are warmed to 35?-37?C by a heater/circulator that pumps water through the Cell Warmer in which the In-Line Cells are located. After filling the receptor chambers of the cells and purging the system of bubbles, the subject compound is then placed in the donor chambers of the cells. From that time, the fluid is collected in the vials of the fraction collector at user set time intervals. The vials are taken for analysis manually after the sampling time has elapsed.

Overall pricing for the ILC07 System is dependent on the configuration of the In-Line Cells used.