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18906011628
當(dāng)前位置：> 供求商機(jī)> CKMT1 Human/ 重組人肌酸激酶MM同工酶I型
| Synonyms | Creatine kinase M-type, EC 2.7.3.2, Creatine kinase M chain, M-CK, CKM, CKMM, CKMMITI. |
| Introduction | Creatine Kinase MM is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. |
| Description | CKMT1 Human Recombinant without C-terminal Lysine on both chains produced in Pichia Pastoris is a glycosylated 47kDa polypeptide chain having an identical amino acid sequence compared to the native enzyme, purified under non-denaturing conditions and reacts with polyclonal antibodies to MM Isoenzyme in ELISA. The CKMT1 is purified by proprietary chromatographic techniques. |
| Source | Pichia Pastoris. |
| Physical Appearance | Sterile Filtered colourless liquid formulation. |
| Formulation | CKMT1 contains 0.01M Tris-HCl, 0.075M NaCl, 10mM beta-mercaptoethanol, 50% glycerol, 0.1% sodium azide, pH 7.2. |
| Stability | CKMT1 although stable at 15°C for 7 days, should be stored desiccated below -18°C. Please prevent freeze-thaw cycles. |
| Purity | Greater than 95.0% as determined by a） Analysis by RP-HPLC b） Analysis by SDS-PAGE |
| Biological Activity | The biological activity measured by the enzymatic activity of Creatine phosphokinase procedure No.45-UV, 1IU-1 μmole creatine phosphate was 537IU/mg at 37 degrees celsius. |
| Usage | Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
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