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概述
描述	TUBB3 Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. TUBB3 plays a critical role in proper axon guidance and mantainance.
別名	TUBB3, CDCBM, Beta III Tubulin, Class III beta-tubulin, TUBB4, Tubulin, beta 3, Tubulin beta-III, Tubulin beta-3 chain, Tubulin beta-4 chain, Tubulin, beta 3 class III, CFEOM3A
克隆類別	Polyclonal
反應(yīng)種屬	Human, Mouse, Rat
來源宿主	Rabbit
應(yīng)用	WB 1:1000-1:5000 IHC 1:50-1:200
特異性	Tubulin beta Antibody detects endogenous levels of total Tubulin beta

性能
保存方法	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
濃度	1mg/ml
分子量	55kDa
功能	Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon guidance and mantainance.
純化方法	Immunogen affinity purified
亞細(xì)胞定位	Cytoplasm,Cytoskeleton,
組織專一性	Expression is primarily restricted to central and peripheral nervous system. Greatly increased expression in most cancerous tissues.
序列	MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSYRALTVPELTMFDAKNMM AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS EYYQDATAEEEGEMYEDDEEESEAQGPK

實驗結(jié)果圖

Western blot analysis of Tubulin beta expression in Mouse Brain, whole cell lysates,The lane on the left is treated with the antigen-specific peptide.