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Source

Mouse

Applications

WB,IHC,IF,

Reactivity

Human,Rat,Mouse

Dilution

WB: 1:1000-3000; IF 1:200; IHC 1:50-300

Storage

-20°C/1 year

Specificity

The antibody detects endogenous COX IV protein.

Source/Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogen

Recombinant Protein of Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

Uniprot No

P13073

Alternative names

COX IV, COX4

Form

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Clonality

Monoclonal

Background

cytochrome c oxidase subunit 4I1(COX4I1) Homo sapiens Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes

Mol.Wt (Da)

19577

Concentration

1 mg/ml