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C4a/b rabbit pAb
  • C4a/b rabbit pAb
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更新時間:2025-03-10 21:00:08

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SourceRabbitApplicationsWB,IHC,ELISAReactivityHumanDilutionWB:1:500-1:2000
  • Source

    Rabbit

  • Applications

    WB,IHC,ELISA

  • Reactivity

    Human

  • Dilution

    WB: 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    C4a/b Polyclonal Antibody detects endogenous levels of C4a/b protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from the Internal region of human C4A/C4B. AA range:721-770

  • Uniprot No

    P0C0L4/P0C0L5

  • Alternative names

    C4A; CO4; CPAMD2; Complement C4-A; Acidic complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2; C4B; CO4; CPAMD3; Complement C4-B; Basic complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    complement C4A (Rodgers blood group)(C4A) Homo sapiens This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain is cleaved to release C4 anaphylatoxin, an antimicrobial peptide and a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided

  • Other

    C4A/C4B, Complement C4-A/Complement C4-B; Acidic complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2; C4B; CO4; CPAMD3; Complement C4-B; Basic complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3

  • Mol.Wt (Da)

    192771

  • Concentration

    1 mg/ml

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