精品国产亚洲国产亚洲,久热中文在线观看精品视频,成人三级av黄色按摩,亚洲AV无码乱码国产麻豆

BPS Bioscience Inc.
中級會員 | 第3年

當前位置:BPS Bioscience Inc.>>PDE Assay Kits>> 79573PDE4B (Dog) Assay Kit

PDE4B (Dog) Assay Kit

參  考  價面議
具體成交價以合同協(xié)議為準

產(chǎn)品型號79573

品       牌BPS Bioscience

廠商性質(zhì)生產(chǎn)商

所  在  地

更新時間:2023-11-11 23:05:40瀏覽次數(shù):209次

聯(lián)系我時,請告知來自 化工儀器網(wǎng)
同類優(yōu)質(zhì)產(chǎn)品更多>
●Purchase●DescriptionPhosphodiesterases(PDEs)playanimportantroleindynamicregulationofcAMPandcGMPsignaling
Purchase
Description

Phosphodiesterases (PDEs) play an important role in dynamic regulation of cAMP and cGMP signaling. PDE4 selective inhibitors are currently in clinical trials for the treatment of diseases related to inflammatory disorders. Altered activity of PDE4B has been associated with schizophrenia and bipolar disorder. It has also recently been found to modulate cognition, as reduction in PDE4B activity improves memory and long-term plasticity in mouse models.

The dog PDE4B (dPDE4B) Assay Kit is designed for identification of inhibitors of dog PDE4b using fluorescence polarization. The assay is based on the binding of a fluorescent nucleotide monophosphate generated by canine PDE4B to the binding agent.

Phosphodiesterases catalyze the hydrolysis of the phosphodiester bond in dye-labeled cyclic monophosphates. Beads selectively bind the phosphate group in the nucleotide product. This increases the size of the nucleotide relative to unreacted cyclic monophosphate. In the polarization assay, dye molecules with absorption transition vectors parallel to the linearly-polarized excitation light are selectively excited. Dyes attached to the rapidly-rotating cyclic monophosphates will obtain random orientations and emit light with low polarization. Dyes attached to the slowly-rotating nucleotide-bead complexes will not have time to reorient and therefore will emit highly polarized light.

The Dog PDE4B Assay Kit comes in a convenient 96-well format, with purified dPDE4B enzyme, fluorescently labeled dPDE4B substrate (cAMP), binding agent, and PDE assay buffer for 100 enzyme reactions. The key to the Dog PDE4B Assay Kit is the specific binding agent. Using this kit, only two simple steps on a microtiter plate are required for dPDE4B reactions. First, the fluorescently labeled cAMP is incubated with a sample containing dPDE4B for 1 hour. Second, a binding agent is added to the reaction mix to produce a change in fluorescent polarization that can then be measured using a fluorescence reader equipped for the measurement of fluorescence polarization.

會員登錄

×

請輸入賬號

請輸入密碼

=

請輸驗證碼

收藏該商鋪

X
該信息已收藏!
標簽:
保存成功

(空格分隔,最多3個,單個標簽最多10個字符)

常用:

提示

X
您的留言已提交成功!我們將在第一時間回復(fù)您~
撥打電話
在線留言
两人爽爽爽无码免费视频| 白丝袜子宫啊啊啊不要了| 一区二中文字幕在线看国产一区| 从后面进入嗯啊视频| 日本二区在线观看| 好嗨哟直播看片在线观看| 日本不卡高清视频在线播放| 狗狗大鸡巴狂操美女| 日韩欧美一级特黄大片欧| 日本一二区视频在线观看| 性一交一乱一乱一区二区| 国产精品视频一区二区三区分享| 青青操成人版性视频| 中文字幕精品字幕一区二区三区| 国产一区二区三区免费观在线| 美女被插b在线观看| 日韩午夜免费av在线| 鸡巴操骚逼视频播放| 中文字幕在线资源第一页| 国产日女人视频在线观看| 日韩人妻精品一区二区三区| 午夜成人理论片在线观看| 胸大裸体美女视频| 少妇精品久久久一区二区免费| 男插女逼啪啪啪软件| 亚洲精品影片一区二区三区| 久久久一区二区三区日本| 内射后入在线观看一区| 国奴精品毛片av一区二区三区| 欧美男女舔逼舔鸡巴视频| 97人人澡人人爽人人揉| 美女被大屌操大骚逼| 99爱国产精品免费视频| 国产精品亚洲一区二区三区极品| 裸毛片视频在线视频| 粉嫩小穴被大鸡巴操视频在线观看| 免费黄色 操逼视频| 精品国产自在现线看| ai换脸久久一区二区亚洲av| 精品免费福利片国产| 国产品无码一区二区三区在线|