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BPS Bioscience Inc.
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KRAS (G12D), Isoform A, His-Tag, GppNHp-Loaded Recombinant
  • KRAS (G12D), Isoform A, His-Tag, GppNHp-Loaded Recombinant
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更新時(shí)間：2024-12-02 21:00:07

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●Purchase●DescriptionRecombinanthumanKRAS(KRASproto-oncogeneGTPase),isoforma,encompassingaminoacids2-186(end)
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Description

Recombinant human KRAS (KRAS proto-oncogene GTPase), isoform a, encompassing amino acids 2-186(end). This construct contains an N-terminal His-tag (6xHis) followed by an optimal TEV protease target sequence that allows cleavage of the His-tag from the protein (TEV: tobacco etch virus cysteine protease BPS Bioscience #50308). The protein also contains mutation of interest G12D. The protein was affinity purified and loaded with GppNHp, a non-hydrolyzable GTP analog. Unbound GppNHp was removed by spin column. Ready for use in KRAS-RAF binding studies or inhibitor assays.

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Synonyms
GTPase KRas, K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras, GTPase KRas, N-terminally processed, KRAS2, RASK2

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