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92055ESRecombinant Human HGF Protein
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  • 上海市 所在地

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10μg815元99 件 可售

訪問(wèn)次數(shù):155更新時(shí)間:2024-03-17 18:46:37

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初級(jí)會(huì)員·12年
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曹女士
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產(chǎn)品簡(jiǎn)介
供貨周期 現(xiàn)貨 應(yīng)用領(lǐng)域 醫(yī)療衛(wèi)生,生物產(chǎn)業(yè)
HGF is a potent, mesenchymally-derived mitogen for mature parenchymal hepatocytes, and acts as a growth factor for a broad spectrum of tissues and cell types. HGF signals through a transmembrane tyros
產(chǎn)品介紹

Product Description

HGF is a potent, mesenchymally-derived mitogen for mature parenchymal hepatocytes, and acts as a growth factor for a broad spectrum of tissues and cell types. HGF signals through a transmembrane tyrosine kinase receptor known as MET. Activities of HGF include the induction of cell proliferation, motility, morphogenesis, inhibition of cell growth, and enhancement of neuron survival. HGF is a crucial mitogen for liver regeneration processes, especially after partial hepatectomy and other liver injuries. HGF, also known as scatter factor and hepatopoietin A, is a pleiotropic protein in the plasminogen subfamily of S1 peptidases. It is a multidomain molecule that includes an N-terminal PAN/APPLE?like domain, four Kringle domains, and a serine proteinase-like domain that has no detectable protease activity.

 

Product Properties

Synonyms

Scatter Factor (SF), Hepatopoietin (HPTA)

Accession

P14210

Gene ID

3082

Source

CHO-derived Human HGF proteinGln32-Ser728

Molecular Weight

88~90 kDa (single chain), 59~61 kDa (alpha chain), 30~34 kDa (beta chain), on SDS-PAGE under reducing conditions.

Tag

None

Purity

95% by SDS-PAGE.

Biological Activity

ED50 < 10.0 ng/ml, measured in a cell proliferation assay using 4MBr5 cells, corresponding to a specific activity of > 1.0 × 105 units/mg.

Endotoxin

0.2 EU per 1μg of the protein by the LAL method.

Formulation

Lyophilized after extensive dialysis against PBS.

Reconstitution

It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH?O or PBS up to 100 μg/ml. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added.

 

Shipping and Storage

The products are shipped with ice pack and can be stored at -80 for 1 year.

week, 2 to 8 °C under sterile conditions after reconstitution.

3 months, -20 °C under sterile conditions after reconstitution.

Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

 

Cautions

  1. Avoid repeated freeze-thaw cycles.

  2. For your safety and health, please wear lab coats and disposable gloves for operation.

  3. For research use only.

 

HB240227

 




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