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Normal Human Small Airway Epithelial Cells

人小細(xì)道上皮細(xì)胞

Proliferating Normal Human Small Airway Epithelial Cells-P0

人小細(xì)道上皮細(xì)胞-P0

Proliferating Normal Human Small Airway Epithelial Cells-P1

人小細(xì)道上皮細(xì)胞-P1

Proliferating Normal Human Small Airway Epithelial Cells- P1 (NhSAE-P1) are initially isolated as NhSAE-P0 cells from the fifth generation of bronchi down to small airways near 1mm in diameter. The NhSAE-P0 cells are then expanded on plastic using BEGM, CRC or Dual Smad expansion media to isolate out an homogenous basal cell population known as NhSAE-P1.

Proliferating NhSAE-P1 cells have been characterized by morphological assessment by light microscopy. The NhSAE-P1 homogenous basal cell population was then further QC tested after differentiating the NhSAE-P1 cells into ciliated, non-ciliated and goblet cells. These differentiated cells were characterized and Air/Liquid Interface culture (ALI) validated by immunofluorescence using protein markers for Cilia (acetylated tubulin), mucin (MUC5AC), tight junctions (Zonula Occludens-1), and basal cells (cytokeratin-5).

The NhSAE-P1 cells are guaranteed to have minimum population doublings of at least 20 (from P1 to P3) following the instructions and conditions provided by Novabiosis.

THESE PRODUCTS ARE FOR RESEARCH USE ONLY and NOT approved for use in humans or clinical diagnostic testing.

Normal Human Small Airway Epithelial Cells

人小細(xì)道上皮細(xì)胞

PBMC分離試劑盒

人外周血單個(gè)核細(xì)胞分離試劑盒PBMC分離液

人PBMC分離試劑盒 人PBMC分離液

猴外周血單個(gè)核細(xì)胞分離試劑盒PBMC分離液

猴PBMC分離試劑盒 猴PBMC分離液

比格犬外周血單個(gè)核細(xì)胞分離試劑盒PBMC分離液

比格犬PBMC分離試劑盒 比格犬PBMC分離液

狗外周血單個(gè)核細(xì)胞分離試劑盒PBMC分離液

狗PBMC分離試劑盒 狗PBMC分離液

大鼠外周血單個(gè)核細(xì)胞分離試劑盒PBMC分離液

大鼠PBMC分離試劑盒 大鼠PBMC分離液

小鼠外周血單個(gè)核細(xì)胞分離試劑盒PBMC分離液

小鼠PBMC分離試劑盒 小鼠PBMC分離液

兔外周血單個(gè)核細(xì)胞分離試劑盒PBMC分離液

兔PBMC分離試劑盒 兔PBMC分離液

豬外周血單個(gè)核細(xì)胞分離試劑盒PBMC分離液

豬PBMC分離試劑盒 豬PBMC分離液

豚鼠外周血單個(gè)核細(xì)胞分離試劑盒PBMC分離液

豚鼠PBMC分離試劑盒 豚鼠PBMC分離液

骨髓單個(gè)核細(xì)胞分離試劑盒Bone Marrow Mononuclear Cells Isolation Kit

脾單個(gè)核細(xì)胞分離試劑盒 Spleen Mononuclear Cells Isolation Kit

紅細(xì)胞分離試劑盒

人紅細(xì)胞分離試劑盒 紅細(xì)胞分離液

猴紅細(xì)胞分離試劑盒 紅細(xì)胞分離液

比格犬紅細(xì)胞分離試劑盒 紅細(xì)胞分離液

大鼠紅細(xì)胞分離試劑盒 紅細(xì)胞分離液

小鼠紅細(xì)胞分離試劑盒 紅細(xì)胞分離液

ADME相關(guān)產(chǎn)品

Ⅰ相代謝穩(wěn)定性試劑盒

Ⅱ相代謝穩(wěn)定性試劑盒

CYP450 酶代謝表型研究試劑盒（化學(xué)抑制法/7種抑制劑）

CYP450 酶代謝表型研究試劑盒（重組酶法/7種酶）

CYP450 酶代謝表型研究試劑盒（重組酶法/單酶）

酶抑制（IC50）研究試劑盒（7種特異性底物）

酶抑制（IC50）研究試劑盒（單個(gè)酶）

NADPH再生系統(tǒng)

UGT孵育系統(tǒng)

0.1M PBS

肝微粒體（人，猴，犬，大鼠，小鼠）

肝S9（人，猴，犬，大鼠，小鼠）

肝原代細(xì)胞（人，猴，犬，大鼠，小鼠）

CYP450（CYP1A2，CYP2A6，CYP2B6，CYP2C8，CYP2C9，CYP2C19，CYP2D6，CYP2E1，CYP3A4）

UGT酶

探針底物，代謝產(chǎn)物，抑制劑（CYP1A2，CYP2A6，CYP2B6，CYP2C8，CYP2C9，CYP2C19，CYP2D6，CYP2E1，CYP3A4）

ADME服務(wù)項(xiàng)目

肝微粒體代謝穩(wěn)定性（人，猴，犬，大鼠，小鼠）

肝細(xì)胞代謝穩(wěn)定性試驗(yàn)（人，猴，犬，大鼠，小鼠）

代謝表型研究

代謝產(chǎn)物鑒定

代謝途徑鑒定

種屬比較研究

CYPP450抑制實(shí)驗(yàn)（CYP1A2，CYP2A6，CYP2C9，CYP2C19，CYP2D6，CYP2E1，CYP3A4）

CYPP450誘導(dǎo)實(shí)驗(yàn)

血漿蛋白結(jié)合率測(cè)定

血漿穩(wěn)定性試驗(yàn)

跨膜轉(zhuǎn)運(yùn)試驗(yàn)

藥物-藥物相互作用

毒理學(xué)研究

Innovative Reagents for Innovative Research

匯智和源致力于為創(chuàng)新藥企業(yè)及生命科學(xué)研究機(jī)構(gòu)提供高品質(zhì)的生物試劑。