Caspase-10 B/D Polyclonal Antibody
抗體，也叫免疫球蛋白（Ig），是一種能特異性結(jié)合抗原的糖蛋白，而抗原是在易感染動(dòng)物體內(nèi)引發(fā)抗體產(chǎn)生的物質(zhì)。在體內(nèi)，抗體是由于外源性分子的侵襲而產(chǎn)生的?？贵w以一個(gè)或者多個(gè)Y字形單體存在，每個(gè)Y字形單體由4條多肽鏈組成，包含兩條相同的重鏈和兩條相同的輕鏈。輕鏈和重鏈?zhǔn)歉鶕?jù)它們的分子量大小來命名的。Y字形結(jié)構(gòu)的頂端是可變區(qū)，為抗原結(jié)合部位。任何一個(gè)抗體的輕鏈都可以分為κ或λ型（基于小分子多肽結(jié)構(gòu)上的差異），每一個(gè)抗體的重鏈則決定了它的類或型。
保存溫度：-20℃
產(chǎn)品詳情
Caspase-10 B/D Polyclonal Antibody detects endogenous levels of proCaspase-10 B/D protein, actived Caspase-10 (isoform B and D) and Caspase-10(isoform B and D) subunit p12,
免疫原詳細(xì)信息
The antiserum was produced against synthesized peptide derived from human Caspase 10. AA range:430-479
相關(guān)試劑
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
背景
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]。
天津俊達(dá)生物科技有限公司，是從事實(shí)驗(yàn)室耗材銷售的現(xiàn)代化生物科技企業(yè)，公司本著“誠信為本，互利共贏"的核心價(jià)值觀，秉承“以市場為導(dǎo)向，提供服務(wù)"的宗旨為各大院校、科研單位、第三方實(shí)驗(yàn)室檢測機(jī)構(gòu)等提供的產(chǎn)品和服務(wù)。目前公司主要經(jīng)營分子生物學(xué)、細(xì)胞生物學(xué)、免疫學(xué)等生物學(xué)產(chǎn)品，多種實(shí)驗(yàn)室耗材 歡迎垂詢！
備注：圖片僅供參考。僅供科研，不可用于臨床。
化工儀器網(wǎng)